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Ariessence Pure PDGF+ in Montvale, NJ
Ariessence Pure PDGF+ is an advanced regenerative treatment designed to support healing, stimulate collagen production, and improve the overall quality of skin and hair. At the office of Dr. Ran Rubinstein in Montvale, NJ, we use this powerful solution to enhance results after microneedling and laser treatments, and offer it off-label as an injectable solution for facial and neck rejuvenation and for patients experiencing hair thinning.
As one of the first practices in the region to offer Ariessence Pure PDGF+ in multiple applications, we are proud to provide this innovative, growth factor-based treatment to help patients restore smoother skin, address early signs of aging, and improve scalp health.
What Is Ariessence Pure PDGF+?
Ariessence Pure PDGF+ is a proprietary, highly purified solution containing platelet-derived growth factor (PDGF) and other bioactive peptides that promote cell regeneration. It was developed specifically for topical use following skin procedures such as microneedling and laser treatments to support healing, reduce inflammation, and enhance skin renewal.
In Dr. Rubinstein’s Montvale office, Ariessence Pure PDGF+ is also used off-label as a regenerative injectable to stimulate natural collagen production and support hair restoration. These advanced applications are based on growing clinical interest in PDGF’s role in activating fibroblasts, improving skin texture, and strengthening hair follicles.
Benefits of Ariessence Pure PDGF+
Patients in Montvale choose Ariessence Pure PDGF+ for its many benefits:
- Non-blood-based, vegan-friendly alternative to PRP
- No need for a blood draw or lab processing
- Faster healing after skin treatments
- Smoother, firmer skin over time
- Subtle, natural-looking rejuvenation
- Minimal downtime
- Enhances the results of other treatments
When used in a treatment plan curated by Dr. Rubinstein, Ariessence Pure PDGF+ becomes a powerful tool to support long-term skin and hair health.



Ariessence Pure PDGF+ Procedure
How It Works
Platelet-derived growth factor (PDGF) is one of the body’s natural messengers involved in wound healing and tissue repair. When applied topically or injected into the skin, Ariessence Pure PDGF+ can help:
- Increase the production of collagen and elastin
- Improve circulation and nutrient delivery
- Reduce inflammation
- Accelerate healing after procedures
- Revitalize damaged or aging skin
- Promote hair follicle regeneration
PDGF+ is not derived from blood products and does not involve platelet-rich plasma (PRP). Instead, Ariessence uses a laboratory-purified, vegan-sourced peptide complex, making it an excellent alternative for patients who do not want to undergo a blood draw or prefer a more standardized and controlled formula.
Approved and Off-Label Applications
At our Montvale, NJ practice, Ariessence Pure PDGF+ is used in the following ways:
Post-Treatment Topical Application
Ariessence Pure PDGF+ is intended for topical application following microneedling, fractional laser, or other skin resurfacing procedures. It helps soothe the skin and support the body’s natural healing response to achieve faster recovery and better cosmetic outcomes.
Facial and Neck Injections (Off-Label)
Dr. Rubinstein uses PDGF-BB off-label as an injectable biostimulatory treatment to improve skin quality and firmness in the under eyes, face and neck. This technique delivers growth factors directly into the deeper layers of skin, where they can activate fibroblasts and stimulate collagen regeneration.
This treatment is ideal for patients noticing:
- Under eye hollows
- Skin laxity or sagging
- Fine lines and crepey texture
- Mild volume loss
It is a non-surgical option for patients looking to restore youthful skin tone and firmness without fillers or more invasive procedures.
Hair Restoration (Off-Label)
PDGF-BB is also used off-label to help with early hair thinning and loss. When injected into the scalp, the growth factors can help:
- Reinvigorate dormant hair follicles
- Support healthy hair growth cycles
- Improve scalp health and blood flow
This treatment may benefit both men and women experiencing mild to moderate hair thinning or diffuse hair loss, especially when caught early.
Best Candidates of Ariessence Pure PDGF+
Ideal Candidates
You may be a good candidate for Ariessence Pure PDGF+ if you:
- Are undergoing microneedling or laser skin resurfacing
- Want faster healing and better results from your procedure
- Prefer a non-blood-based growth factor treatment
- Are noticing early signs of skin aging, such as under eye hollows, fine lines or skin laxity
- Have mild to moderate hair thinning and are looking for non-surgical options
This treatment is generally safe for all skin types and tones. Dr. Rubinstein will evaluate your goals and medical history to determine if this therapy fits into your personalized treatment plan.
Dr. Rubinstein is highly skilled at knowing what treatments are needed to achieve optimal results. I’ve been going to him for over 15 years and trust him wholeheartedly. He’s exceptional at what he does, a true artist!
I’m a perfectionist I do my research before doing anything to my face or body. He is the best. Educated, experienced, professional. I’ve been going to him for years and never had any problems. He will keep your face looking naturally beautiful.
What to Expect During Treatment
For Post-Treatment Topical Use
Ariessence Pure PDGF+ is applied immediately after microneedling or fractional laser while the skin channels are still open. The solution penetrates deeply, taking advantage of the skin’s heightened permeability to deliver its regenerative ingredients where they are needed most.
For Injections in the Face, Neck, or Scalp
When used as an injectable treatment, a numbing cream may be applied first for comfort. Dr. Rubinstein then uses a very fine needle to deliver small amounts of the PDGF+ solution into targeted areas. Treatments usually take 30 minutes.
Multiple sessions may be recommended for optimal results, particularly for hair restoration or collagen stimulation. Sessions are typically spaced 4 to 8 weeks apart.
Recovery and Results
Topical Use Recovery
There is no additional downtime associated with the topical application of Ariessence. In fact, many patients experience reduced redness and irritation following their procedure. Most people return to normal activities the next day.
Injection Recovery
Recovery from injectable use is minimal. You may experience some redness, swelling, or mild bruising at the injection sites, which typically resolve within a few days. Some patients may have mild swelling and redness that lasts for an additional few weeks, which is a sign of collagen stimulation and new blood vessel formation. Aftercare instructions will be provided.
Expected Results
- Improved skin tone and texture within as little as a few weeks
- Gradual improvement in firmness and fine lines over several months
- For hair restoration, early signs of regrowth may appear in 2–3 months
- Best results often seen after a series of treatments
Combination Treatments
Ariessence Pure PDGF+ is often used in conjunction with other rejuvenating treatments at our Montvale practice. Common combinations include:
- Microneedling + Ariessence PDGF+: Enhances collagen production and shortens recovery time
- Laser Resurfacing + Ariessence PDGF+: Supports skin regeneration and reduces downtime
- Injectables (e.g., Botox, dermal Fillers) + PDGF-BB: Complements volume restoration with improved skin tone
- Hair Restoration + PDGF-BB: Customized scalp protocols to optimize hair regrowth
Dr. Rubinstein will tailor your treatment plan based on your goals, skin type, and overall health.

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Safety and Side Effects
Ariessence Pure PDGF+ is considered safe for most individuals. It is free of blood derivatives, parabens, and animal byproducts. The topical version is intended for post-procedural use, while the injectable applications are off-label and performed only by qualified professionals like Dr. Rubinstein.
Possible side effects include:
- Mild irritation or tingling (topical use)
- Temporary redness, swelling, or bruising (injectable use)
- Rare allergic reactions
Patients with active infections, autoimmune disorders, or bleeding disorders should discuss risks with Dr. Rubinstein before treatment.

Ariessence vs. PRP: What's the Difference?
Both Ariessence Pure PDGF+ and PRP (platelet-rich plasma) use growth factors to rejuvenate the skin and scalp, but there are important differences:
- Source: PRP is derived from the patient’s blood; Ariessence is synthetically formulated
- Consistency: Ariessence offers standardized concentration and purity; PRP results can vary by patient
- Convenience: No blood draw or spinning process is needed for Ariessence
- Use Cases: Ariessence is better for patients who prefer a non-invasive, needle-free, or vegan solution
Some patients may respond better to one treatment over the other. Dr. Rubinstein can guide you through the pros and cons of each.
Pricing and Consultation
The cost of Ariessence Pure PDGF+ treatment varies based on the application type (topical or injectable), treatment area, and number of sessions required. During your consultation with Dr. Rubinstein, we will provide a detailed treatment plan and cost estimate tailored to your needs.
To get started, please contact our Montvale, NJ, office to schedule your consultation.
Why Choose Dr. Ran Rubinstein in Montvale, NJ
Dr. Ran Rubinstein is a double board-certified facial plastic surgeon known for his experience in aesthetic and regenerative treatments. He stays at the forefront of medical innovation, offering his Montvale patients access to advanced therapies like Ariessence Pure PDGF+ to support skin health and longevity.
At our Montvale office, you will find:
- Customized treatment plans tailored to your goals
- Experienced medical team and professional care
- Access to the latest technologies and non-surgical solutions
Whether you are seeking skin rejuvenation, accelerated healing, or support for thinning hair, our team is here to guide you every step of the way.
Frequently Asked Questions
Is Ariessence Pure PDGF+ FDA approved?
Ariessence is listed with the FDA as a cosmetic product and like most other cosmetic products, it has not received nor does it require approval by the FDA. While Ariessence is not FDA approved, the pure PDGF component of Ariessence is also present in 4 medical therapeutic products that are FDA approved. The pure PDGF in Ariessence is exactly the same, and from the same manufacturing line and meets the same exacting standards, as the pure PDGF in the 4 FDA approved products.
How many treatments will I need?
This varies by patient and goal. Many patients undergo a series of 2 to 3 treatments spaced 4 to 8 weeks apart for best results, especially for hair or facial rejuvenation.
Can Ariessence be used with other treatments?
Yes. Ariessence pairs well with microneedling, laser therapy, Botox, fillers, and biostimulants like Sculptra and Radiesse for combination therapy. Dr. Rubinstein will help you decide what combination works best for your goals.
Is there any downtime?
Minimal. Topical use involves no additional downtime. Injections may cause mild redness or swelling, which usually resolves within a few weeks.
Who should not use Ariessence?
Patients with active infections, bleeding disorders, or severe allergies may not be good candidates. Dr. Rubinstein will review your medical history before proceeding.
Does Ariessence replace PRP?
It is a strong alternative to PRP but not necessarily a replacement. Ariessence provides a consistent, non-blood-based option for patients who want the benefits of growth factors without the need for blood draws.
How soon will I see results?
Improvements may be noticeable within a few weeks, with continued improvement over several months as collagen builds or hair follicles respond.
Is Ariessence painful?
Topical use is pain-free. Injectable treatments may cause slight discomfort, but numbing cream is used to improve comfort.
Is Ariessence safe for all skin types?
Yes. Ariessence Pure PDGF+ is generally safe for all skin tones and types, but a consultation is essential to ensure proper use.
How do I book an Ariessence treatment?
Contact our Montvale, NJ, office to schedule your consultation and learn more about how Ariessence Pure PDGF+ can benefit your skin or hair health.